Laboratory of in Vitro Metabolism and Separation Techniques

Title: In Vitro Evaluation of the Effects of Emerging Contaminants on Human Cytochrome P450: Prediction of Toxicokinetic Parameters and Xenobiotic–Drug Interactions

Funding: FAPESP

Grant Number: 2024/20783-4 (for more information, click here)

Project Duration: 01/08/2025 to 31/07/2028

 

 

Title: In Vitro Enantioselective Evaluation of the Effects of Chiral Pesticides on the Major Human Cytochrome P450 Enzymes Involved in Drug Metabolism: In Vitro–In Vivo Correlation and Prediction of Pesticide–Drug Interactions

Funding agency: FAPESP

Grant Number: 2021/10098-4 (for more information, click here)

Project Duration: 01/02/2022 to 31/07/2024

 

Title: Development of chromatographic/electrophoretic methods for further application in in vitro enzyme inhibition studies and prediction of drug interactions of chiral pesticides - Phase 2

Funding agency: FAPESP

Grant Number: 2018 / 07534-4 (for more information click here )

Project Duration: 08/01/2018 to 03/31/2021

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Title: Development of chromatographic/electrophoretic methods for subsequent application in in vitro studies of enzyme inhibition and drug interactions of chiral pesticides

Funding agency: FAPESP

Grant Number: 2016 / 07597-0 (for more information click here )

Project Duration: 08/01/2016 to 07/30/2018

Title: Development and validation of chromatographic and electrophoretic methods for further application in in vitro biotransformation and metabolism studies - Phase 2

Funding agency: FAPESP

Grant Number: 2013 / 17658-9 (for more information click here )

Project Duration: 12/01/2013 to 11/30/2015

Title: Development and validation of chromatographic and electrophoretic methods for further application in in vitro biotransformation and metabolism studies

Funding agency: FAPESP

Grant Number: 2011 / 17508-1 (for more information click here )

Project Duration: 12/01/2011 to 11/30/2013

Title: Enantioselective analysis of chiral metabolites using fungi in the biotransformation process

Funding agency: CNPq - Universal Project

Grant Number: 470845 / 2009-0

Project Duration: 11/26/2009 to 11/25/2011

Title: Evaluation of the use of endophytic fungi obtained from plants and filamentous fungi obtained from soil in obtaining pharmacologically active chiral metabolites

Funding agency: FAPESP

Grant Number: 2009 / 06132-0 (for more information click here )

Project Duration: 10/01/2009 to 9/30/2011